Benfica  | 1-0 | Borussia Dortmund | Estadio do Dragao | 14 Feb | h. 20:45 |
Paris Saint Germain  | 4-0 | Barcellona | Parco dei Principi | 14 Feb | h. 20:45 |
Bayern Monaco  | 5-1 | Arsenal | 15 Feb | h. 20:45 | |
Real Madrid  | 3-1 | Napoli | Santiago Bernabeu | 15 Feb | h. 20:45 |
| Bayer Leverkusen | 2-4 | Atletico Madrid | BayArena | 21 Feb | h. 20:45 |
Manchester City  | 5-3 | Monaco | City of Manchester Stadium | 21 Feb | h. 20:45 |
| Porto | 0-2 | Juventus | Estadio do Dragao | 22 Feb | h. 20:45 |
Siviglia  | 2-1 | Leicester | Ramon Sanchez Pizjuan | 22 Feb | h. 20:45 |