Borussia Dortmund  | 0-1 |  Tottenham | Signal Iduna Park | 5 Mar | h. 21:00 |
| Real Madrid | 1-4 |  Ajax | Santiago Bernabeu | 5 Mar | h. 21:00 |
| Paris Saint Germain | 1-3 | Manchester United | Parco dei Principi | 6 Mar | h. 21:00 |
Porto  | 3-1 (d.t.s) | Roma | Estadio do Dragao | 6 Mar | h. 21:00 |
Juventus  | 3-0 |  Atletico Madrid | Allianz Stadium | 12 Mar | h. 21:00 |
Manchester City  | 7-0 | Schalke 04 | City of Manchester Stadium | 12 Mar | h. 21:00 |
| Barcellona | 5-1 | Olympique Lione | Camp Nou | 13 Mar | h. 21:00 |
Bayern Monaco  | 1-3 |  Liverpool | Allianz Arena | 13 Mar | h. 21:00 |