| Sassuolo U19 | 0-1 | Atalanta U19 | Enzo Ricci | 9 Mar | h.11:00 |
| Verona U19 | 1-0 | Milan U19 | Synergy Stadium | 9 Mar | h.11:00 |
| Genoa U19 | 1-0 | Lecce U19 | Comunale Chittolina | 9 Mar | h.13:00 |
| Inter U19 | 2-2 | Juventus U19 | Konami Youth Development Centre in Memory of Giacinto Facchetti | 9 Mar | h.13:00 |
| Torino U19 | 4-0 | Monza U19 | Valentino Mazzola | 9 Mar | h.15:00 |
| Fiorentina U19 | 1-6 | Roma U19 | Viola Park | 10 Mar | h.11:00 |
| Empoli U19 | 3-0 | Cagliari U19 | C.S. Petroio di Vinci | 10 Mar | h.13:00 |
| Frosinone U19 | 4-0 | Sampdoria U19 | C.S. Città dello Sport | 10 Mar | h.13:00 |
| Lazio U19 | 3-0 | Bologna U19 | C.S. Formello, Campo Mirko Fersini | 11 Mar | h.15:00 |