| Verona | 2-1 | Bologna | Marcantonio Bentegodi | 21 Apr | h.20:45 |
| Salernitana | 3-0 | Sassuolo | Arechi | 22 Apr | h.15:00 |
| Lazio | 0-1 | Torino | Olimpico | 22 Apr | h.18:00 |
| Sampdoria | 1-1 | Spezia | Luigi Ferraris | 22 Apr | h.20:45 |
| Empoli | 0-3 | Inter | Carlo Castellani Computer Gross Arena | 23 Apr | h.12:30 |
| Monza | 3-2 | Fiorentina | U-Power Stadium | 23 Apr | h.15:00 |
| Udinese | 3-0 | Cremonese | Bluenergy Stadium | 23 Apr | h.15:00 |
| Milan | 2-0 | Lecce | Giuseppe Meazza | 23 Apr | h.18:00 |
| Juventus | 0-1 | Napoli | Allianz Stadium | 23 Apr | h.20:45 |
| Atalanta | 3-1 | Roma | Gewiss Stadium | 24 Apr | h.20:45 |