| Empoli | 0-1 | Bologna | Carlo Castellani Computer Gross Arena | 15 Mar | h.20:45 |
| Monza | 1-0 | Cagliari | U-Power Stadium | 16 Mar | h.15:00 |
| Udinese | 0-2 | Torino | Bluenergy Stadium - Stadio Friuli | 16 Mar | h.15:00 |
| Salernitana | 0-1 | Lecce | Arechi | 16 Mar | h.18:00 |
| Frosinone | 2-3 | Lazio | Benito Stirpe | 16 Mar | h.20:45 |
| Juventus | 0-0 | Genoa | Allianz Stadium | 17 Mar | h.12:30 |
| Verona | 1-3 | Milan | Marcantonio Bentegodi | 17 Mar | h.15:00 |
| Roma | 1-0 | Sassuolo | Olimpico | 17 Mar | h.18:00 |
| Inter | 1-1 | Napoli | Giuseppe Meazza | 17 Mar | h.20:45 |
| Atalanta | 2-3 | Fiorentina | Gewiss Stadium | 2 Giu | h.18:00 |